Publications

2025

Rest-to-work and work-to-rest transients of interstitial PO2 in spinotrapezius muscle of young and old male rats

Aleksander S Golub, William H Nugent, Roland N Pittman, Bjorn K Song
Physiological Reports
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2025

Low-volume Resuscitation with VS-101, a Next-Generation PEGylated HBOC, Improves Survival after Severe Hemorrhagic Shock in Rats

William H Nugent, Kim D Vandegriff, Ashok Malavalli, Forest R Sheppard, Bjorn K Song
Shock
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2025

Oxygen transport across the lifespan of male Sprague Dawley rats

William H Nugent, Aleksander S Golub, Roland N Pittman, Bjorn K Song
Biogerontology
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2024

Oxygenation through oral Ox66 in a two-hit rodent model of respiratory distress

Bjorn K Song, Danuel A Carr, Erica D Bruce, William H Nugent
Artifical Cells, Nanomedicine, Biotechnology
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2023

Exchange Transfusion with VS-101: A New Pegylated-HB Designed to Restore Perfusion and Increase O2 Carrying Capacity

William H Nugent, Forest R Sheppard, Kim D Vandegriff, William M Schindler, Ashok Malavalli, Bjorn K Song
Shock
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2023

Novel transdermal curcumin therapeutic preserves endothelial barrier function in a high-dose LPS rat model

William H. Nugent, Danuel A. Carr, Joel Friedman, Bjorn K. Song
Artifical Cells, Nanomedicine, Biotechnology
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2022

Evaluation of an Injectable, Solid-State, Oxygen-Delivering Compound (Ox66) in a Rodent Model of Pulmonary Dysfunction-Induced Hypoxia

Danuel A Carr, William H Nugent, Erica D Bruce, Bjorn K Song
Military Medicine
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2021

Gavage approach to oxygen supplementation with oxygen therapeutic Ox66™ in a hypoventilation rodent model of respiratory distress

William H Nugent, Danuel A Carr, Rosa MacBryde, Erica D Bruce, Bjorn K Song
Artifical Cells, Nanomedicine, Biotechnology
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2021

Spike of interstitial PO2 produced by a twitch in rhythmically contracted muscle

Aleksander S Golub, William H Nugent, Bjorn K Song
Physiological Reports
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2020

Systemic and microvascular comparison of Lactated Ringer’s solution, VIR-HBOC, and alpha-alpha crosslinked haemoglobin-based oxygen carrier in a rat 10% topload model

Bjorn K Song, W Richard Light, Kim D Vandegriff, Joe Tucker, William H Nugent
Artifical Cells, Nanomedicine, Biotechnology
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2020

Improved Hemodynamic Recovery and 72-Hour Survival Following Low-Volume Resuscitation with a PEGylated Carboxyhemoglobin in a Rat Model of Severe Hemorrhagic Shock

Antoni Macko, Forest R Sheppard, William H Nugent, Abe Abuchowski, Bjorn K Song
Military Medicine
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2020

Physiological and microvascular responses to hemoglobin concentration-targeted hemolytic anemia in rats

William H Nugent, Danuel A Carr, Antoni R Macko, Bjorn K Song
Journal of Applied Physiology
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2020

Microvascular and Systemic Impact of Resuscitation with PEGylated Carboxyhemoglobin-Based Oxygen Carrier or Hetastarch in a Rat Model of Transient Hemorrhagic Shock

William H Nugent, Forest R Sheppard, Michael A Dubick, Ramon F Cestero, Daniel N Darlington, Ronald Jubin, Abe Abuchowski, Bjorn K Song
Shock
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2019

Microvascular and systemic responses to novel PEGylated carboxyhaemoglobin-based oxygen carrier in a rat model of vaso-occlusive crisis

William H Nugent, Ronald Jubin, Peter J Buontempo, Friedericke Kazo, Bjorn K Song
Artifical Cells, Nanomedicine, Biotechnology
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2019

Effects of Sanguinate® on Systemic and Microcirculatory Variables in a Model of Prolonged Hemorrhagic Shock

William H Nugent, Ramon F Cestero, Kevin Ward, Ronald Jubin, Abe Abuchowski, Bjorn K Song
Shock
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2019

Oral ingestion of a novel oxygenating compound, Ox66™, is non-toxic and has the potential to increase oxygenation

Fan Zhang, Grace V Aquino, Amjad Dabi, William H Nugent, Bjorn K Song, Erica D Bruce
Food and Chemical Toxicology
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2016

Simultaneous sampling of tissue oxygenation and oxygen consumption in skeletal muscle

William H Nugent, Bjorn K Song, Roland N Pittman, Aleksander S Golub
Microvascular Research
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2014

Effects of a hemoglobin-based oxygen carrier (HBOC-201) and derivatives with altered oxygen affinity and viscosity on systemic and microcirculatory variables in a top-load rat model

Bjorn Kyungsuck Song, William H Nugent, Paula F Moon-Massat, Roland N Pittman
Microvascular Research
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2014

A paradigm shift for local blood flow regulation

Aleksander S Golub , Roland N Pittman
Microvascular Research
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2014

Muscle contraction increases interstitial nitric oxide as predicted by a new model of local blood flow regulation

Aleksander S Golub, Bjorn K Song, Roland N Pittman
Journal of Physiology
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2013

Bang-bang model for regulation of local blood flow

Aleksander S Golub, Roland N Pittman
Microcirculation
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2013

Effects of top-loading a zero-link bovine hemoglobin, OxyVita, on systemic and microcirculatory variables

Bjorn Kyungsuck Song 1, William H Nugent, Paula F Moon-Massat, Charles R Auker, Richard McCarron, Roland N Pittman
Military Medicine
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2012

Oxygen dependence of respiration in rat spinotrapezius muscle in situ

Aleksander S Golub, Roland N Pittman
American Journal of Physiology: Heart and Circulatory Physiology
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2011

The rate of O₂ loss from mesenteric arterioles is not unusually high

Aleksander S Golub, Bjorn K Song, Roland N Pittman
American Journal of Physiology: Heart and Circulatory Physiology
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2011

Phosphorescence quenching microrespirometry of skeletal muscle in situ

Aleksander S Golub, Michael A Tevald, Roland N Pittman
American Journal of Physiology: Heart and Circulatory Physiology
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2005

Erythrocyte-associated transients in PO2 revealed in capillaries of rat mesentery

Aleksander S Golub, Roland N Pittman
American Journal of Physiology: Heart and Circulatory Physiology
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